We want to take this opportunity to remember the beautiful life and spirit of a very special person that we were so fortunate to have gotten to know throughout this project. Her name is Bette Martin, and she passed away after her long battle with cancer.
You can read Bette’s obituary here.
Bette was enthusiastic about the mission of Facing Cancer Together from the beginning, and openly shared her story in the hopes that others would find some courage to face their own situation with hope.
She helped to illustrate the fear that a person really faces when they hear the words: “You have cancer,” and the inner struggle that a person experiences when you're faced with a new perspective on how to live.
She wrote in her blog titled, "How now shall I live?":
"My relationship with God has been strengthened and continues to grow. I think that the timing of events since the diagnosis has confirmed God’s presence in my life. Evidence of divine intervention has been instrumental in clarifying my trust in God’s love and concern for me. There is much more growth needed in this area of my life. I thank the Creator every morning that I open my eyes and see the light of another day, allowing for the development of a deeper relationship with Him."
She taught us to explore what’s out there, like alternative therapies for mind and body healing, and to tap into our spirituality for strength and guidance.
We thankBette for her honesty, courage, and partnership.
She will be deeply missed but her story will live on in the countless people that she touched throughout her life. Our thoughts and prayers are with Bette's family and friends.
-The Facing Cancer Together team
Ann Durr Lyon of Camp Hill, PA passed away at her home on Thursday surrounded by family on February 7th.
Our Facing Cancer Together team is so fortunate to have met Ann and her husband Walter during an interview for this series. She shared her powerful story about fighting breast cancer and being able to give herself permission to try something new in her life. She encouraged other cancer survivors to be brave and try something new as well.
Ann said, "Being encouraged to do something I'd never done before was so strengthening and so important to me. Everybody with cancer should know that this is one of the possibilities." Adding, "It's just the business of hope."
In our interview, she also reflected on her life's adventures and how grateful she was for her loving husband and family, saying: "85 years... almost every day there was something special."
Remembering Ann Durr Lyon:
Trailblazing educator, political activist and beloved HACC Professor, Ann Durr Lyon of Camp Hill, PA passed away at her home on Thursday surrounded by family on February 7th.
Ann was born in Birmingham, AL the eldest of four daughters of famed civil rights activists Clifford and Virginia (Foster) Durr of Montgomery, AL.
Over three decades as Professor of Sociology at HACC, Ann taught a variety of popular courses. She especially enjoyed teaching about racial inequality and the history of civil rights. She founded, developed and led the Human Service Program at HACC and attained Emeritus status. She also Co-Founded the Temple University Graduate Program in Social Work in Harrisburg.
Ann founded the Harrisburg Civil Rights Oral History Project. She served as an East Pennsboro Township Commissioner, on the West Shore Council of Governments and the Cumberland Co. Board of Assistance. Ann represented local voters as a Democratic Committeewoman, was active in the league of Women's Voters and the National Council of Jewish Women and helped begin the Head Start program in Perry County
Ann is survived by her husband, Walter A. Lyon, of Mechanicsburg; daughter, Nan Lyon of Columbia, MD,, three sons, Cliff and Paul Lyon, wife Mel of Salt Lake City, James Lyon and wife Diane and six grandchildren; Brittany, Jane, Otto, Greth, Lilly and Sophie
A memorial service will be held 10 a.m. Saturday March 2nd at the Bethany Village East Side Community Center (entrance 1E).
In lieu of flowers memorial donations can be made to:
The Ann Durr Lyon Human Service Student Scholarship Fund
℅ The HACC Foundation
1 HACC Drive
Harrisburg, PA 17110
HERSHEY, PA–A compound that stimulates the production of a tumor-fighting protein may improve the usefulness of the protein in cancer therapy, according to a team of researchers.
TRAIL is a natural antitumor protein that suppresses tumor development during immune surveillance, the immune system’s process of patrolling the body for cancer cells. This process is lost during cancer progression, which leads to uncontrolled growth and spread of tumors.
The ability of TRAIL to initiate cell death selectively in cancer cells has led to ongoing clinical trials with artificially-created TRAIL or antibody proteins that mimic its action. Use of the TRAIL protein as a drug has shown that it is safe, but there have been some issues, including stability of the protein, cost of the drug, and the ability of the drug to distribute throughout the body and get into tumors, especially in the brain.
“The TRAIL pathway is a powerful way to suppress tumors but current approaches have limitations that we have been trying to overcome to unleash an effective and selective cancer therapy,” said Dr. Wafik El-Deiry, professor of medicine and chief of the hematology/oncology division, Penn State College of Medicine. “The TRAIL biochemical cell death pathway naturally lends itself as a drug target to restore anti-tumor immunity.”
Researchers have identified a compound called TRAIL-inducing Compound 10 (TIC10) as a potential solution. TIC10 stimulates the tumor suppression capabilities of TRAIL in both normal and tumor tissues, including in the brain, and induces tumor cell death in mice. They report their findings in the journal Science Translational Medicine.
TIC10 is a small molecule. This organic compound binds to a protein and alters what the protein does.
Stimulation of TRAIL protein is sustained in both tumor and normal cells, with the normal cells contributing to the TIC10-induced cancer cell death through a bystander effect. It is effective in cancer cell samples and cell lines resistant to conventional therapies.
“I was surprised and impressed that we were able to do this,” El-Deiry said. “Using a small molecule to significantly boost and overcome limitations of the TRAIL pathway appears to be a promising way to address difficult to treat cancers using a safe mechanism already used in those with a normal effective immune system. This candidate new drug, a first-in-its-class, shows activity against a broad range of tumor types in mice and appears safe at this stage.”
New treatments are needed for advanced cancer, as more than half a million people in the United States will die of cancer in 2013.
“We have enough preclinical information to support the rationale for testing this new drug in the clinic,” El-Deiry said.
TIC10 seems to be nontoxic to normal cells or mice even at doses 10 times higher that an observed therapeutic dose, however more research needs to be completed to satisfy FDA requirements prior to initiation of clinical testing.
Other researchers are Joshua E. Allen, David T. Dicker, Akshal S. Patel, Nathan G. Dolloff, Kimberly A. Scata, Wenge Wang, all of Penn State Hershey Cancer Institute; Gabriel Krigsfeld, Patrick A. Mayes, Luv Patel, University of Pennsylvania School of Medicine; Evangelos Messaris, Department of Surgery, Penn State College Medicine; Jun-Ying Zhou and Gen Sheng Wu, Wayne State University School of Medicine.
This study was funded by the American Cancer Society, Penn State Hershey Cancer Institute and the National Institutes of Health.
Located on the campus of Penn State Milton S. Hershey Medical Center in Hershey, Pa., Penn State College of Medicine boasts a portfolio of more than $106 million in funded research. Projects range from the development of artificial organs and advanced diagnostics to groundbreaking cancer treatments and understanding the fundamental causes of disease. Enrolling its first students in 1967, the College of Medicine has more than 1,600 students and trainees in medicine, nursing, the health professions and biomedical research on its campus.
witf has been chosen by the American Cancer Society, East Central Division Awards Committee as the 2012 recipient of the Division Citation Award.
“As we move to a Digital Age for healthcare technology, specifically for medical records and health information exchange, it requires a different workforce,” explains Martin Ciccocioppo, Vice President of Research with the Hospital and Healthsystem Association of Pennsylvania.
(Lancaster) -- Many times, the first thing a person does when experiencing some unusual medical symptoms is head to the Internet.
But using a search engine may not always be the best way to diagnose an ailment or health-related issue.
witf's Megan Lello spoke with Dr. Paul Conslato, medical director for Lancaster General Medical Group, about how to responsibly read through diagnoses online. Dr. Conslato says that some independent learning on symptoms that they are experiencing is usually a good idea.
Listen to their conversation:
Dr. Conslato says, “The reality is, a more informed patient usually leads to a more productive engagement where the physician is acting as a partner in finding a solution to a person’s healthcare needs,” he explains.
But, with every potential innovation in healthcare there are some downsides. What he sees on an infrequent basis is a heightened concern about symptoms.
“An e-Patient is someone that is empowered, engaged, equipped, and enabled,” says Christine Amy from Aligning Forces for Quality --- South Central Pennsylvania. Amy works to help people become better so-called “e-Patients” by using technology to stay informed about their health.
Amy highlights some of the characteristics of an engaged patient in this video.
The healthcare industry is just starting to incorporate electronic medical records, patient portals, and apps into their practices. And, although it is just the beginning, Dr. Karen Jones, an Internist & Medical Director for Quality and Innovation at WellSpan Health, says that the future is not too far out in changing how care is delivered and received. Watch the video here.
“For me, the most exciting part of the Digital Age in health care is the potential we have to help people understand and have more control of their health care,” says Dr. Jones.
And, check out this video to learn more about how medical apps are streamlining care and are helping patients become more engaged in their care.
Where do you turn for information about a diagnosis or symptoms you're experiencing? Do you feel that doing some research before a visit with your doctor makes it a more meaningful interaction? Please share your thoughts in a comment below.
October is National Breast Cancer Awareness Month. One doesn't have to look far to see a pink ribbon, buildings cast in pink light or fountains flowing with pink water. The color pink is associated with the cause so much during the month that everyone knows exactly what it signifies.
When the campaign began in October 1985, the focus was on early detection of breast cancer. That's still an important message, but billions of dollars have been donated and contributed toward breast cancer research and treatment.
Progress has been made. About 2% fewer breast cancers were detected between 1999 and 2005 and death rates from breast cancer have been dropping since 1990.
This episode of Radio Smart Talk explores the impact of National Breast Cancer Awareness Month in the past and into the future.
We'll also look into current statistics, treatments, research, and what the future holds.
Program guests include Pat Halpin-Murphy, the president and founder of the Pennsylvania Breast Cancer Coalition, Leigh Hurst, the founder of Feel Your Boobies, and Dr. Ronald Hempling, a gynecologic oncologist with WellSpan Health.
Listen to the program:
Cancer is the epidemic of modern times. Unlike other diseases that have plagued people throughout history like tuberculosis and polio, we haven’t yet discovered a vaccine against it. One of the most common manifestations of this disease is breast cancer, which affects not only one in eight women, but also thousands of men in the United States.
“An e-Patient is someone that is empowered, engaged, equipped, and enabled,” says Christine Amy from Aligning Forces for Quality --- South Central Pennsylvania.
“When I think about the ways that doctors are accessing medical applications and patient data now, I think of keywords like value and convenience,” says Dr. Michael Ripchinski, Chief Medical Information Officer and Family Physician at Lancaster General Health. “It is valuable for them to have access to record electronically so they can can continue to deliver care for patient even in the off hours. And, it is convenient that they don’t have to travel back to office to initiate or continue care for their patients.”